Accounts Payable and Accrued Expenses - Schedule of Accounts Payable and Accrued Expenses (Detail) - USD ($) $ in Thousands	Dec. 31, 2020	Dec. 31, 2019
Payables And Accruals [Abstract]
Accounts payable	$ 4,893	$ 9,100
Accrued research projects	6,194	6,637
Accrued professional fees	839	635
Accrued compensation and benefits	4,955	3,293
Total	$ 16,881	$ 19,665