XML 56 R42.htm IDEA: XBRL DOCUMENT v3.20.4
Summary of Significant Accounting Policies - Additional Information (Detail)
$ in Thousands
12 Months Ended 59 Months Ended
Jan. 01, 2020
agreement
Jan. 01, 2018
contract
Dec. 31, 2020
USD ($)
Institution
item
segment
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Dec. 31, 2018
USD ($)
Jun. 30, 2020
Jan. 01, 2019
USD ($)
lease
Dec. 31, 2017
USD ($)
Summary Of Significant Accounting Policies [Line Items]                  
Number of revenue related contracts | contract   2              
Prepaid R&D expense | $     $ 11,286 $ 8,498          
Expected volatility, minimum     71.80% 71.10% 82.60%        
Expected volatility, maximum     74.80% 75.20% 92.80%        
Expected dividend yield     0.00% 0.00% 0.00%        
Cumulative effect adjustment | $     $ 249,001 $ 186,713 $ 133,630 $ 133,630     $ 86,780
Number of renewable terms     1            
Lease, Practical Expedient, Use of Hindsight [true false]     true            
Lease, Practical Expedients, Package [true false]     true            
Number of operating segments | segment     1            
Number of collaboration and licensing agreements | agreement 3                
Stamford Operating Lease [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Operating Lease, renewable term     5 years            
Annual incremental borrowing rate     7.00% 7.00%          
Stamford Operating Lease [Member] | ASC 842 [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of operating lease | lease               1  
Number of renewable terms     1            
Operating Lease, renewable term     5 years            
Annual incremental borrowing rate     7.00%            
Stamford Operating Lease [Member] | ASC 842 [Member] | Cumulative Effect, Period of Adoption, Adjustment [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Cumulative effect adjustment | $               $ 0  
New Stamford Lease [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of renewable terms     1            
Operating Lease, renewable term             5 years    
Annual incremental borrowing rate     7.00%            
New Stamford Lease [Member] | ASC 842 [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of renewable terms     1            
Operating Lease, renewable term     5 years            
Employee Options [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Expected life of options (in years)     6 years 3 months            
Expected volatility, minimum     72.00% 71.00% 83.00%        
Expected volatility, maximum     75.00% 75.00% 93.00%        
Expected volatility           75.00%      
Expected dividend yield     0.00% 0.00% 0.00%        
Non Employee Stock Option [Member] | Maximum [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Expected life of options (in years)     10 years            
Cash And Cash Equivalents And Marketable Securities [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of financial institutions | Institution     4