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Stockholders' Equity - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Aug. 20, 2019
Jul. 29, 2019
Mar. 20, 2019
Jul. 23, 2018
Jul. 18, 2018
Apr. 05, 2017
Mar. 30, 2017
Dec. 31, 2019
Jul. 31, 2019
May 31, 2019
Dec. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Apr. 04, 2019
Subsidiary Sale Of Stock [Line Items]                              
Common stock, shares authorized               100,000,000     100,000,000 100,000,000 100,000,000    
Common stock, par value               $ 0.001     $ 0.001 $ 0.001 $ 0.001    
Preferred stock, shares authorized               5,000,000     5,000,000 5,000,000 5,000,000    
Preferred stock, par value               $ 0.001     $ 0.001 $ 0.001 $ 0.001    
Common stock, shares outstanding               46,720,225     39,547,558 46,720,225 39,547,558    
Common stock, shares issued               46,720,225     39,547,558 46,720,225 39,547,558    
Preferred stock, shares issued               0     0 0 0    
Preferred Stock Shares Outstanding               0     0 0 0    
Restricted stock units vested shares                     83,791        
Unregistered common stock exchanged for consulting services                       $ 197      
Compensation expense                       10,300 $ 8,401 $ 6,330  
Shareholder Consulting Agreement [Member]                              
Subsidiary Sale Of Stock [Line Items]                              
Price per share     $ 19.37                        
Number of shares of unregistered common stock exchanged for consulting services     10,195                        
Consulting services performance period     6 months                        
General and Administrative [Member]                              
Subsidiary Sale Of Stock [Line Items]                              
Compensation expense                       5,094 $ 4,482 $ 3,897  
General and Administrative [Member] | Shareholder Consulting Agreement [Member]                              
Subsidiary Sale Of Stock [Line Items]                              
Compensation expense                       $ 197      
Non-Exclusive License Agreement                              
Subsidiary Sale Of Stock [Line Items]                              
Upfront fee $ 8,000                            
Upfront fee payable, cash 4,000                            
Upfront fee payable, stock $ 4,000                            
Price per share $ 23.42                            
Share price average, Determination period 30 days                            
Percentage of payment, stock 50.00%                            
Maximum [Member]                              
Subsidiary Sale Of Stock [Line Items]                              
Aggregate offering price of securities                             $ 300,000
Follow-on Public Offering [Member]                              
Subsidiary Sale Of Stock [Line Items]                              
Price per share               $ 23.00     $ 19.00 $ 23.00 $ 19.00 $ 18.00  
Common Stock [Member]                              
Subsidiary Sale Of Stock [Line Items]                              
Restricted stock units vested shares               36,666   74,166   110,832 83,791    
Common stock, shares issued                       6,325,000 5,175,000 5,117,500  
Number of shares of unregistered common stock exchanged for consulting services                       10,195      
Common Stock [Member] | Non-Exclusive License Agreement                              
Subsidiary Sale Of Stock [Line Items]                              
Upfront fee payable, stock $ 4,000                            
Common stock, shares issued 170,793                            
Common Stock [Member] | Follow-on Public Offering [Member]                              
Subsidiary Sale Of Stock [Line Items]                              
Common stock, shares issued                 6,325,000            
Common stock, shares issued         5,175,000   5,117,500                
Price per share         $ 19.00   $ 18.00   $ 23.00            
Proceeds from issuance of common stock net of underwriting discounts, commissions and estimated offering expenses   $ 136,498                          
Proceeds from issuance of common stock net of underwriting discounts and offering costs       $ 92,063   $ 86,224                  
Common Stock [Member] | Underwriter's Over-Allotment [Member]                              
Subsidiary Sale Of Stock [Line Items]                              
Common stock, shares issued   825,000   675,000 675,000 667,500 667,500   825,000            
Underwriting discounts, commission and offering expenses   $ 8,977   $ 6,262   $ 5,891