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Summary of Significant Accounting Policies - Additional Information (Detail)
$ in Thousands
12 Months Ended
Dec. 31, 2019
USD ($)
segment
Institution
Dec. 31, 2018
USD ($)
Dec. 31, 2017
Jan. 01, 2017
USD ($)
Summary Of Significant Accounting Policies [Line Items]        
Prepaid R&D expense $ 8,498 $ 4,377    
Expected volatility, minimum 71.10% 82.60% 75.30%  
Expected volatility, maximum 75.20% 92.80% 84.50%  
Expected dividend yield 0.00% 0.00% 0.00%  
Number of operating segments | segment 1      
Operating lease liability $ 4,319      
ASU 2016-09 [Member]        
Summary Of Significant Accounting Policies [Line Items]        
Cumulative effect adjustment       $ 45
Employee Options [Member]        
Summary Of Significant Accounting Policies [Line Items]        
Expected life of options (in years) 6 years 3 months      
Expected volatility, minimum 71.00% 83.00% 75.00%  
Expected volatility, maximum 75.00% 93.00% 85.00%  
Expected volatility   75.00% 79.00%  
Expected dividend yield 0.00%      
Non Employee Stock Option [Member] | Maximum [Member]        
Summary Of Significant Accounting Policies [Line Items]        
Expected life of options (in years) 10 years      
Cash And Cash Equivalents And Marketable Securities [Member]        
Summary Of Significant Accounting Policies [Line Items]        
Number of financial institutions | Institution 4