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Condensed Statements of Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Revenue:        
Total revenue $ 5,785 $ 5,062 $ 15,375 $ 7,936
Operating expenses:        
Research and development 35,992 22,303 83,956 52,732
General and administrative 4,226 3,227 13,128 10,609
Total operating expenses 40,218 25,530 97,084 63,341
Operating loss (34,433) (20,468) (81,709) (55,405)
Other income 1,261 1,002 3,297 1,780
Loss before benefit from income taxes (33,172) (19,466) (78,412) (53,625)
Benefit from income taxes 330 66 650 264
Net loss $ (32,842) $ (19,400) $ (77,762) $ (53,361)
Net loss per share:        
Basic and Diluted $ (0.74) $ (0.51) $ (1.88) $ (1.54)
Weighted average shares:        
Basic and Diluted 44,517,134 38,034,216 41,314,044 34,696,835
Other comprehensive income, net of tax of $0:        
Change in unrealized gains (losses) on available-for- sale marketable securities $ (12) $ 70 $ 267 $ 83
Total comprehensive loss (32,854) (19,330) (77,495) (53,278)
License and Milestone Fees [Member]        
Revenue:        
Total revenue $ 5,785 5,029 15,235 7,903
Clinical Compound Revenue [Member]        
Revenue:        
Total revenue   $ 33 $ 140 $ 33