Income Taxes (Tables)

12 Months Ended

Dec. 31, 2015

Income Tax Disclosure [Abstract]

Components of Income Taxes (Benefit)

The Company’s benefit from income taxes is as follows:

	December 31,
	2015			2014			2013
Current:
Federal	$	—		$	—		$	—
State		(397	)		(201	)		(30	)
		(397	)		(201	)		(30	)
Deferred:
Federal		—			—			—
State		—			—			—
		—			—			—
Benefit from income taxes	$	(397	)	$	(201	)	$	(30	)

Schedule of Reconciliation of Income Taxes Computed Using U.S. Federal Statutory Rate to that Reflected in Operations

A reconciliation of income taxes computed using the U.S. federal statutory rate to that reflected in operations is as follows:

	December 31,
	2015			2014			2013
Income taxes using U.S. federal statutory rate		34.00	%		34.00	%		34.00	%
State income taxes, net of federal benefit		5.95	%		5.23	%		6.03	%
Impact of R&D tax credit on effective tax rate		3.14	%		3.03	%		12.04	%
Stock option shortfalls and cancellations		-0.03	%		-0.69	%		0.00	%
Permanent items and other		-0.41	%		-0.57	%		-1.42	%
Change in valuation allowance		-41.07	%		-39.88	%		-49.90	%
		1.58	%		1.12	%		0.75	%

Schedule of Significant Components of Company's Deferred Tax Assets

Significant components of the Company’s deferred tax assets are as follows:

	December 31,
	2015			2014
Net operating loss carryforwards	$	36,217		$	27,094
Federal and state tax credits		4,315			3,508
Accelerated depreciation		1,206			1,018
Deferred revenue		—			566
Stock-based compensation expense		1,106			333
Other		189			197
		43,033			32,716
Valuation allowance		(43,033	)		(32,716	)
Net deferred tax asset	$	—		$	—