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Commitments and Contingencies - Additional Information (Detail)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Nov. 01, 2024
USD ($)
Sep. 26, 2024
USD ($)
Jul. 28, 2023
USD ($)
May 11, 2023
USD ($)
Aug. 31, 2019
USD ($)
Jul. 31, 2021
Jul. 31, 2019
agreement
Mar. 31, 2025
USD ($)
Mar. 31, 2024
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Sep. 25, 2024
USD ($)
Other Commitments [Line Items]                          
Research and development               $ 3,111 $ 3,721 $ 23,650 $ 15,866    
Operating lease cost               24 22 $ 96 90    
Option to extend                   true      
Operating lease right-of-use assets               199   $ 216 262    
Operating lease liabilities               280   304      
Operating lease liability - current               106   103 93    
Operating cash outflows relating to operating leases               50 49 197 194    
Non-cash lease payments               95          
Future non-cash lease payments               312   343      
Cara Therapeutics, Inc.                          
Other Commitments [Line Items]                          
Research and development               319 21,964 32,805 108,510 $ 91,879  
Operating Lease, renewable term       5 years                  
Operating lease right-of-use assets               0   0 4,864    
Operating lease liabilities               0   0      
Operating cash outflows relating to operating leases                   4,363 $ 1,992    
Cara Therapeutics, Inc. | New Corporate Headquarters Office Space [Member]                          
Other Commitments [Line Items]                          
Lease, annual fixed rent       $ 1,300                  
Lease, fixed rent, annual increase, percent       2.50%                  
Option to extend       true                  
Lessee, operating lease, discount rate, basis spread on variable rate       7.75%             7.75%    
Debt Instrument, Variable Interest Rate, Type [Extensible Enumeration]       us-gaap:SecuredOvernightFinancingRateSofrMember                  
Discount rate - operating leases                     12.83%    
Lessee, operating lease, incentives     $ 2,900                    
Operating lease right-of-use assets     6,779                    
Operating lease liabilities     $ 6,672                    
Lease incentives reimbursed                   2,094 $ 808    
Lease incentives remaining to be reimbursed                   0      
Operating Lease, expense                   766 $ 524    
Lessee, operating lease, discount rate, variable rate basis, floor       2.75%             2.75%    
Cara Therapeutics, Inc. | New Corporate Headquarters Office Space [Member] | Research and Development [Member]                          
Other Commitments [Line Items]                          
Operating Lease, expense                   368 $ 367    
Cara Therapeutics, Inc. | New Corporate Headquarters Office Space [Member] | General and Administrative [Member]                          
Other Commitments [Line Items]                          
Operating Lease, expense                   398 157    
Cara Therapeutics, Inc. | Assignment of New Lease                          
Other Commitments [Line Items]                          
Operating lease, cash lease payments   $ 3,238                      
Operating lease, release payments   1,125                      
Operating lease, non-cash lease payments $ 3,417                        
Operating lease, initial direct costs capitalized   577                      
Operating lease liability - current   3,417                     $ 7,780
Operating cash outflows relating to operating leases   $ 4,363                      
Impairment charge in ROU asset                   4,274      
Future non-cash lease payments                   0      
Cara Therapeutics, Inc. | Old Stamford Operating Lease [Member]                          
Other Commitments [Line Items]                          
Operating lease cost                     1,624 1,624  
Cara Therapeutics, Inc. | Old Stamford Operating Lease [Member] | Research and Development [Member]                          
Other Commitments [Line Items]                          
Operating lease cost                     1,137 1,137  
Cara Therapeutics, Inc. | Old Stamford Operating Lease [Member] | General and Administrative [Member]                          
Other Commitments [Line Items]                          
Operating lease cost                     487 487  
Cara Therapeutics, Inc. | Patheon [Member]                          
Other Commitments [Line Items]                          
Reduced demand payment for manufacturing commitments                     1,700    
Cara Therapeutics, Inc. | New Stamford Lease [Member]                          
Other Commitments [Line Items]                          
Letter of credit amount outstanding                     1,500    
Cara Therapeutics, Inc. | Non-Exclusive License Agreement [Member] | Enteris Biopharma, Inc. [Member]                          
Other Commitments [Line Items]                          
Upfront fee         $ 8,000                
Payment of milestone payment               $ 0 $ 0 $ 0 $ 0 5,000  
Research and development                       $ 5,000  
License agreement expiration period, first commercial sale         10 years                
Upfront fee payment, cash         $ 4,000                
Upfront fee payment, stock         $ 4,000                
Agreement termination period for material breach         60 days                
Agreement termination period for material breach of a payment obligation         30 days                
Agreement termination period for challenged patent rights         30 days                
Agreement termination period prior to first regulatory approval         30 days                
Agreement termination period after first regulatory approval         60 days                
Cara Therapeutics, Inc. | MSA [Member] | Patheon and Patheon Manufacturing Services LLC [Member]                          
Other Commitments [Line Items]                          
Number of related product agreements | agreement             2            
Cara Therapeutics, Inc. | MSA [Member] | Patheon [Member]                          
Other Commitments [Line Items]                          
Agreement renewal term             2 years            
Agreement initial term, expiration date             Dec. 31, 2024            
Agreement expiration date             Dec. 31, 2026            
Cara Therapeutics, Inc. | API Commercial Supply Agreement - PPL [Member]                          
Other Commitments [Line Items]                          
Agreement renewal term           5 years              
Cara Therapeutics, Inc. | MSA or Product Agreement [Member] | Patheon [Member]                          
Other Commitments [Line Items]                          
Agreement initial term, expiration date             Either party may terminate the MSA or a Product Agreement upon written notice if the other party (1) has failed to remedy a material breach within a specified time or (2) is declared insolvent or bankrupt, voluntarily files a petition of bankruptcy or assigns such agreement for the benefit of creditors. The Company may terminate a Product Agreement (a) upon 90 days’ prior written notice if any governmental agency takes any action that prevents the Company from selling the relevant product in the relevant territory, (b) upon six months’ prior written notice if it does not intend to order manufacturing services due to a product’s discontinuance in the market, or (c) upon 90 days’ prior written notice if it determines that the manufacture or supply of a product likely infringes third-party rights. Patheon may terminate the MSA or a Product Agreement (i) upon six months’ prior written notice if the Company assigns such agreement to an assignee that is unacceptable to Patheon for certain reasons, or (ii) upon 30 days’ prior written notice if, after the first year of commercial sales, the Company forecasts zero volume for 12 months.            
Termination notice effective period upon government agency restrictions             90 days            
Termination notice effective period upon discontinuance in the market             6 months            
Termination notice period if likely infringes on third-party rights             90 days            
Termination notice period if assignee is unacceptable             6 months            
Termination notice period if zero volume is forecasted after first year of commercial sales             30 days