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Summary of Significant Accounting Policies - Additional Information (Detail)
$ in Thousands
3 Months Ended 12 Months Ended
Apr. 15, 2025
shares
Apr. 01, 2025
shares
Dec. 19, 2024
shares
Mar. 31, 2025
USD ($)
shares
Mar. 31, 2024
USD ($)
Dec. 31, 2024
USD ($)
item
shares
Dec. 31, 2023
USD ($)
item
shares
Dec. 31, 2022
USD ($)
item
Apr. 14, 2025
shares
Dec. 18, 2024
shares
Jun. 07, 2024
shares
Jun. 06, 2024
shares
Basis of Presentation [Line Items]                        
Common stock, shares authorized | shares       58,251,629   58,251,629 58,251,629          
Expected life of options (in years)         5 years 10 months 24 days 5 years 10 months 24 days 6 years 1 month 6 days          
Expected dividend yield         0.00% 0.00% 0.00%          
Impairment of long-lived assets           $ 0 $ 0          
Depreciation and amortization       $ 24 $ 24 $ 95 $ 95          
Cara Therapeutics, Inc.                        
Basis of Presentation [Line Items]                        
Reverse stock split ratio     0.083                  
Common stock, shares authorized | shares     16,666,667 16,666,667   16,666,667 8,333,333     200,000,000 200,000,000 100,000,000
Prepaid R&D expense       $ 5   $ 13 $ 7,245          
Expected dividend yield         0.00% 0.00% 0.00% 0.00%        
Impairment of long-lived assets           $ 4,274 $ 0 $ 0        
Inventory write-down       0 $ 0 2,963            
Unrecognized tax provisions           0 0          
Unrecognized tax benefits, related interest and penalties           0 0 0        
Depreciation and amortization       $ 0 $ 42 $ 192 $ 259 $ 248        
Cara Therapeutics, Inc. | CSL Vifor and CKDP Agreements [Member] | License and milestone fees [Member]                        
Basis of Presentation [Line Items]                        
Number of performance obligations for revenue recognized | item           1 1 1        
Cara Therapeutics, Inc. | Stock Options                        
Basis of Presentation [Line Items]                        
Expected life of options (in years)           6 years 3 months 6 years 3 months 6 years 3 months        
Expected dividend yield           0.00% 0.00% 0.00%        
Subsequent Event | Cara Therapeutics, Inc.                        
Basis of Presentation [Line Items]                        
Reverse stock split ratio 0.333 0.33                    
Common stock, shares authorized | shares 150,000,000 150,000,000             16,666,667      
Fractional Shares Issued For Reverse Stock Split | shares 0 0