Commitments and Contingencies (Tables)

3 Months Ended

12 Months Ended

Mar. 31, 2025

Dec. 31, 2024

Schedule of Other Information related to Stamford Lease, Lease Amendment and New Lease

The components of lease costs, which are included within general and administrative expenses in the Company’s condensed statements of operations and comprehensive loss were as follows (in thousands):

	For the Three Months Ended March 31,
	2025		2024
Lease costs:
Operating lease cost	$	24	$	22
Variable lease cost		22		21
Total lease costs	$	46		43

The components of lease costs, which are included within general and administrative expenses in the Company’s statements of operations were as follows (in thousands):

	For the Year Ended
	December 31,
	2024		2023
Lease costs:
Operating lease cost	$	96	$	90
Variable lease cost		80		83
Total lease costs	$	176		173

Schedule of Future Minimum Lease Payments under Non-cancellable Operating Leases, Reconciliation of Undiscounted Cash Flows to the Operating Lease Liabilities

As of March 31, 2025, the maturities of the Company’s operating lease liabilities were as follows (in thousands):

Year Ended December 31,	Amount
2025 (remaining nine months)	$	95
2026		129
2027		88
Total lease payments		312
Less: imputed interest		(32)
Present value of lease liabilities		280
Less: operating lease liabilities, current portion	$	106
Operating lease liabilities, net of current portion	$	174

As of December 31, 2024, the maturities of the Company’s operating lease liabilities were as follows (in thousands):

Year Ended December 31,	Amount
2025	$	126
2026		129
2027		88
Total lease payments		343
Less: imputed interest		(39)
Present value of lease liabilities		304
Less: operating lease liabilities, current portion	$	103
Operating lease liabilities, net of current portion	$	201

Cara Therapeutics, Inc.

Schedule of activity related to the Company's restructuring action

Total restructuring expense recorded during the year ended December 31, 2024	$	5,689
Payments made during the year ended December 31, 2024		(5,515)
Reversal of restructuring provision during the year ended December 31, 2024		(124)
Remaining amount to be paid as of December 31, 2024	$	50

Schedule of Other Information related to Stamford Lease, Lease Amendment and New Lease

	Three Months Ended March 31,
	2025			2024
Cash paid for amounts included in the measurement of lease liabilities:
Operating cash outflows relating to operating leases	$	—		$	—
ROU assets obtained in exchange for new operating lease liabilities	$	—		$	—
Remaining lease term - operating leases (years)		—			10.6
Discount rate - operating leases		—	%		12.8	%

	Year Ended December 31,
	2024			2023
Cash paid for amounts included in the measurement of lease liabilities:
Operating cash outflows relating to operating leases	$	4,363		$	1,992
ROU assets obtained in exchange for new operating lease liabilities	$	—		$	6,779
Remaining lease term - operating leases (years)		—			10.8
Discount rate - operating leases		—	%		12.8	%