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Commitments and Contingencies - Additional Information (Detail)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Nov. 01, 2024
USD ($)
Sep. 26, 2024
USD ($)
Jul. 28, 2023
USD ($)
May 11, 2023
USD ($)
Aug. 31, 2019
USD ($)
Jul. 31, 2021
Jul. 31, 2019
agreement
Sep. 30, 2024
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2024
USD ($)
Sep. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Sep. 25, 2024
USD ($)
Nov. 30, 2023
USD ($)
Other Commitments [Line Items]                                
Accounts payable and accrued expenses               $ 6,622   $ 6,622   $ 25,592 $ 21,540      
Operating Lease, renewable term       5 years                        
Debt Instrument, Variable Interest Rate, Type [Extensible Enumeration]                   us-gaap:SecuredOvernightFinancingRateSofrMember            
Operating lease liabilities                       6,088        
Operating lease right-of-use assets                       4,864 1,551      
Lease incentives                               $ 1,755
Lease incentives reimbursed                       808        
Operating lease liability - current               3,417   $ 3,417     1,918      
Cash payment relating to operating leases               4,363 $ 500 4,363 $ 1,489 $ 1,992 1,957      
New Corporate Headquarters Office Space [Member]                                
Other Commitments [Line Items]                                
Lease, annual fixed rent       $ 1,300                        
Lease, fixed rent, annual increase, percent       2.50%                        
Option to extend       true                        
Operating Lease, renewable term       5 years                        
Lessee, operating lease, discount rate, basis spread on variable rate       7.75%               7.75%        
Discount rate - operating leases       12.83%               12.83%        
Operating lease liabilities     $ 6,672                          
Lessee, operating lease, incentives     2,900                          
Operating lease right-of-use assets     6,779                          
Lease incentives     $ 2,900                          
Lease incentives reimbursed                   2,094            
Lease incentives remaining to be reimbursed                   0            
Operating Lease, expense               241 214 766 214 $ 524        
Lessee, operating lease, discount rate, variable rate basis, floor       2.75%               2.75%        
New Corporate Headquarters Office Space [Member] | Research and Development [Member]                                
Other Commitments [Line Items]                                
Operating Lease, expense                 150 368 150 $ 367        
New Corporate Headquarters Office Space [Member] | General and Administrative [Member]                                
Other Commitments [Line Items]                                
Operating Lease, expense               241 64 398 64 157        
Assignment of New Lease                                
Other Commitments [Line Items]                                
Operating lease, cash lease payments   $ 3,238                            
Operating lease, release payments   1,125                            
Operating lease, initial direct costs capitalized   577                            
Operating lease liability - current   3,417                         $ 7,780  
Cash payment relating to operating leases   $ 4,363                            
Impairment charge in ROU asset               4,274   4,274            
Non-cash lease payments               3,417   3,417            
Assignment of New Lease | Subsequent Event [Member]                                
Other Commitments [Line Items]                                
Operating lease, non-cash lease payments $ 3,417                              
Original Corporate Headquarters Office Space And Amendment [Member]                                
Other Commitments [Line Items]                                
Operating lease cost                       1,624 1,624 $ 1,624    
Original Corporate Headquarters Office Space And Amendment [Member] | Research and Development [Member]                                
Other Commitments [Line Items]                                
Operating Lease, expense                       1,137 1,137 1,137    
Original Corporate Headquarters Office Space And Amendment [Member] | General and Administrative [Member]                                
Other Commitments [Line Items]                                
Operating Lease, expense                       487 487 487    
Patheon and Patheon Manufacturing Services LLC [Member]                                
Other Commitments [Line Items]                                
Reduced demand payment for manufacturing commitments                       1,700        
Old Stamford Operating Lease [Member]                                
Other Commitments [Line Items]                                
Operating lease cost               0 407 0 1,220          
Old Stamford Operating Lease [Member] | Research and Development [Member]                                
Other Commitments [Line Items]                                
Operating lease cost                 285   854          
Old Stamford Operating Lease [Member] | General and Administrative [Member]                                
Other Commitments [Line Items]                                
Operating lease cost                 122   366          
Patheon [Member]                                
Other Commitments [Line Items]                                
Reduced demand payment for manufacturing commitments                       1,700        
New Stamford Lease [Member]                                
Other Commitments [Line Items]                                
Letter of credit amount outstanding               1,500   1,500   1,500        
Non-Exclusive License Agreement [Member] | Enteris Biopharma, Inc. [Member]                                
Other Commitments [Line Items]                                
Payment of milestone payment               $ 0 $ 0 $ 0 $ 0 $ 0 $ 5,000 $ 15,000    
Upfront fee         $ 8,000                      
Upfront fee payment, cash         4,000                      
Upfront fee payment, stock         $ 4,000                      
License agreement expiration period, first commercial sale         10 years                      
Agreement termination period for material breach         60 days                      
Agreement termination period for material breach of a payment obligation         30 days                      
Agreement termination period for challenged patent rights         30 days                      
Agreement termination period prior to first regulatory approval         30 days                      
Agreement termination period after first regulatory approval         60 days                      
MSA [Member] | Patheon and Patheon Manufacturing Services LLC [Member]                                
Other Commitments [Line Items]                                
Number of related product agreements | agreement             2                  
MSA [Member] | Patheon [Member]                                
Other Commitments [Line Items]                                
Agreement renewal term             2 years                  
Agreement initial term, expiration date             Dec. 31, 2024                  
MSA [Member] | Patheon [Member] | Minimum [Member]                                
Other Commitments [Line Items]                                
Termination notice effective period             18 months                  
API Commercial Supply Agreement - PPL [Member]                                
Other Commitments [Line Items]                                
Agreement renewal term           5 years                    
Agreement successive renewal term                   2 years            
MSA or Product Agreement [Member] | Patheon [Member]                                
Other Commitments [Line Items]                                
Agreement initial term, expiration date             Either party may terminate the MSA or a Product Agreement upon written notice if the other party (1) has failed to remedy a material breach within a specified time or (2) is declared insolvent or bankrupt, voluntarily files a petition of bankruptcy or assigns such agreement for the benefit of creditors. The Company may terminate a Product Agreement (a) upon 90 days’ prior written notice if any governmental agency takes any action that prevents the Company from selling the relevant product in the relevant territory, (b) upon six months’ prior written notice if it does not intend to order manufacturing services due to a product’s discontinuance in the market, or (c) upon 90 days’ prior written notice if it determines that the manufacture or supply of a product likely infringes third-party rights. Patheon may terminate the MSA or a Product Agreement (i) upon six months’ prior written notice if the Company assigns such agreement to an assignee that is unacceptable to Patheon for certain reasons, or (ii) upon 30 days’ prior written notice if, after the first year of commercial sales, the Company forecasts zero volume for 12 months.                  
Termination notice effective period upon government agency restrictions             90 days                  
Termination notice effective period upon discontinuance in the market             6 months                  
Termination notice period if likely infringes on third-party rights             90 days                  
Termination notice period if assignee is unacceptable             6 months                  
Termination notice period if zero volume is forecasted after first year of commercial sales             30 days