<SEC-DOCUMENT>0001144204-16-115034-index.html : 20160728
<SEC-HEADER>0001144204-16-115034.hdr.sgml : 20160728
<ACCEPTANCE-DATETIME>20160728163259
ACCESSION NUMBER:		0001144204-16-115034
CONFORMED SUBMISSION TYPE:	SC 13G
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20160728
DATE AS OF CHANGE:		20160728
GROUP MEMBERS:		PETER KOLCHINSKY
GROUP MEMBERS:		RA CAPITAL HEALTHCARE FUND, L.P.

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ARDELYX, INC.
		CENTRAL INDEX KEY:			0001437402
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88209
		FILM NUMBER:		161790561

	BUSINESS ADDRESS:	
		STREET 1:		34175 ARDENWOOD BLVD.
		CITY:			FREMONT
		STATE:			CA
		ZIP:			94555
		BUSINESS PHONE:		510-745-7047

	MAIL ADDRESS:	
		STREET 1:		34175 ARDENWOOD BLVD.
		CITY:			FREMONT
		STATE:			CA
		ZIP:			94555

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NTERYX INC
		DATE OF NAME CHANGE:	20080611

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RA CAPITAL MANAGEMENT, LLC
		CENTRAL INDEX KEY:			0001346824
		IRS NUMBER:				830406777
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G

	BUSINESS ADDRESS:	
		STREET 1:		20 PARK PLAZA, SUITE 1200
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		617-778-2500

	MAIL ADDRESS:	
		STREET 1:		20 PARK PLAZA, SUITE 1200
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G
<SEQUENCE>1
<FILENAME>v445311_sc13g.htm
<DESCRIPTION>SC 13G
<TEXT>
Document 1 - file: v445311_sc13g.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>v445311_ex99-1.htm
<DESCRIPTION>JOINT FILING AGREEMENT
<TEXT>
Document 2 - file: v445311_ex99-1.htm

</DOCUMENT>
</SEC-DOCUMENT>