o
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Rule 13d-1(b)
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x
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Rule 13d-1(c)
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o
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Rule 13d-1(d)
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CUSIP No. 88034G109
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13G
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Page 2 of 7 Pages
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1.
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Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only).
RA Capital Management, LLC
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2.
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Check the Appropriate Box if a Member of a Group (See Instructions)
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(a) o
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(b) o
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3.
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SEC Use Only
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4.
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Citizenship or Place of Organization Massachusetts
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Number of
Shares
Beneficially
Owned by
Each Reporting
Person With
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5.
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Sole Voting Power 1,275,620
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6.
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Shared Voting Power 0
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7.
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Sole Dispositive Power 1,275,620
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8.
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Shared Dispositive Power 0
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9.
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Aggregate Amount Beneficially Owned by Each Reporting Person
1,275,620
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10.
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Check if the Aggregate Amount in Row (9) Excludes
Certain Shares (See Instructions) o
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11.
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Percent of Class Represented by Amount in Row (9)
5.4%
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12.
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Type of Reporting Person (See Instructions)
IA
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CUSIP No. 88034G109
|
13G
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Page 3 of 7 Pages
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1.
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Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only).
Peter Kolchinsky
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2.
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Check the Appropriate Box if a Member of a Group (See Instructions)
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(a) o
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(b) o
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3.
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SEC Use Only
|
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4.
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Citizenship or Place of Organization United States
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Number of
Shares
Beneficially
Owned by
Each Reporting
Person With
|
5.
|
Sole Voting Power 1,275,620
|
||||
6.
|
Shared Voting Power 0
|
|||||
7.
|
Sole Dispositive Power 1,275,620
|
|||||
8.
|
Shared Dispositive Power 0
|
|||||
9.
|
Aggregate Amount Beneficially Owned by Each Reporting Person
1,275,620
|
|||||
10.
|
Check if the Aggregate Amount in Row (9) Excludes
Certain Shares (See Instructions) o
|
|||||
11.
|
Percent of Class Represented by Amount in Row (9)
5.4%
|
|||||
12.
|
Type of Reporting Person (See Instructions)
IN
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CUSIP No. 88034G109
|
13G
|
Page 4 of 7 Pages
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1.
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Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only).
RA Capital Healthcare Fund, L.P.
|
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2.
|
Check the Appropriate Box if a Member of a Group (See Instructions)
|
|||
(a) o
|
||||
(b) o
|
||||
3.
|
SEC Use Only
|
|||
4.
|
Citizenship or Place of Organization Delaware
|
|||
Number of
Shares
Beneficially
Owned by
Each Reporting
Person With
|
5.
|
Sole Voting Power 682,128
|
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6.
|
Shared Voting Power 0
|
|||
7.
|
Sole Dispositive Power 682,128
|
|||
8.
|
Shared Dispositive Power 0
|
|||
9.
|
Aggregate Amount Beneficially Owned by Each Reporting Person
682,128
|
|||
10.
|
Check if the Aggregate Amount in Row (9) Excludes
Certain Shares (See Instructions) o
|
|||
11.
|
Percent of Class Represented by Amount in Row (9)
2.9%
|
|||
12.
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Type of Reporting Person (See Instructions)
PN
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CUSIP No. 88034G109 |
Page 5 of 7 Pages
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Item 3.
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If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
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Item 4.
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Ownership:
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CUSIP No. 88034G109 |
Page 6 of 7 Pages
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Item 5.
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Ownership of Five Percent or Less of a Class:
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Item 6.
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Ownership of More than Five Percent on Behalf of Another Person:
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Item 7.
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Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person:
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Item 8.
|
Identification and Classification of Members of the Group:
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Item 9.
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Notice of Dissolution of Group:
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Item 10.
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Certification:
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CUSIP No. 88034G109 |
Page 7 of 7 Pages
|
DATE: MAY 24, 2011
RA CAPITAL HEALTHCARE FUND, L.P.
By: RA Capital Management, LLC
General Partner
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By:
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/s/ Peter Kolchinsky | |
Peter Kolchinsky
|
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Manager
|
|||
RA CAPITAL MANAGEMENT, LLC
|
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By: | /s/ Peter Kolchinsky | ||
Peter Kolchinsky
Manager
|
|||
PETER KOLCHINSKY
|
|||
/s/ Peter Kolchinsky |
RA CAPITAL HEALTHCARE FUND, L.P.
By: RA Capital Management, LLC
General Partner
|
|||
|
By:
|
/s/ Peter Kolchinsky | |
Peter Kolchinsky
|
|||
Manager
|
|||
RA CAPITAL MANAGEMENT, LLC
|
|||
By: | /s/ Peter Kolchinsky | ||
Peter Kolchinsky
Manager
|
|||
PETER KOLCHINSKY
|
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/s/ Peter Kolchinsky |