The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
5 01 ACQUISITION CORP COM CL 33836P105 7,388 750,000 SH   SOLE   750,000 0 0
89BIO INC COM 282559103 64,903 4,965,769 SH   SOLE   4,965,769 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 25,124 5,014,687 SH   SOLE   5,014,687 0 0
ACUMEN PHARMACEUTICALS INC COM 00509G209 66,050 9,770,773 SH   SOLE   9,770,773 0 0
ADAGIO THERAPEUTICS INC COM 00534A102 36,270 4,995,807 SH   SOLE   4,995,807 0 0
AEROVATE THERAPEUTICS INC COM 008064107 97,432 8,263,982 SH   SOLE   8,263,982 0 0
AKOUOS INC COM 00973J101 19,391 2,281,249 SH   SOLE   2,281,249 0 0
ARYA SCIENCES ACQUISITN CLASS A ORD SHS G31658100 9,700 1,000,000 SH   SOLE   1,000,000 0 0
ASCENDIS PHARMA A/S SPONSORED 04351P101 1,018,110 7,567,900 SH   SOLE   7,567,900 0 0
ASTRIA THERAPEUTICS INC COM 04635X102 6,803 1,262,193 SH   SOLE   1,262,193 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 12,250 1,250,000 SH   SOLE   1,250,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 82,354 10,230,274 SH   SOLE   10,230,274 0 0
BIOMEA FUSION INC COM 09077A106 3,725 500,000 SH   SOLE   500,000 0 0
BLACK DIAMOND THERAPEUTICS INC COM 09203E105 13,804 2,589,904 SH   SOLE   2,589,904 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 11,654 2,378,325 SH   SOLE   2,378,325 0 0
C4 THERAPEUTICS INC COM STK 12529R107 44,358 1,377,569 SH   SOLE   1,377,569 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 40,278 3,577,094 SH   SOLE   3,577,094 0 0
CENTURY THERAPEUTICS INC COM 15673T100 14,498 914,094 SH   SOLE   914,094 0 0
COGENT BIOSCIENCES INC COM 19240Q201 8,800 1,025,641 SH   SOLE   1,025,641 0 0
COMPASS THERAPEUTICS INC COM 20454B104 5,863 1,849,518 SH   SOLE   1,849,518 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 9,556 3,033,603 SH   SOLE   3,033,603 0 0
CONNECT BIOPHARMA HLDGS LTD ADS 207523101 36,004 6,991,003 SH   SOLE   6,991,003 0 0
CUE HEALTH INC COM 229790100 10,058 750,000 SH   SOLE   750,000 0 0
CULLINAN ONCOLOGY INC COM 230031106 5,401 350,000 SH   SOLE   350,000 0 0
CYTEIR THERAPEUTICS INC COM 23284P103 38,095 3,350,506 SH   SOLE   3,350,506 0 0
CYTEK BIOSCIENCES INC COM 23285D109 156,787 9,607,028 SH   SOLE   9,607,028 0 0
DA32 LIFE SCNCE CLASS A COM 23312M106 14,715 1,500,000 SH   SOLE   1,500,000 0 0
DAY ONE BIOPHARMACEUTICALS COM 23954D109 83,670 4,965,588 SH   SOLE   4,965,588 0 0
DESIGN THERAPEUTICS INC COM 25056L103 46,816 2,186,636 SH   SOLE   2,186,636 0 0
DICE THERAPEUTICS INC COM 23345J104 131,838 5,208,911 SH   SOLE   5,208,911 0 0
DYNE THERAPEUTICS INC COM 26818M108 33,352 2,805,045 SH   SOLE   2,805,045 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 39,936 2,613,623 SH   SOLE   2,613,623 0 0
ELIEM THERAPEUTICS INC COM 28658R106 137,558 13,150,849 SH   SOLE   13,150,849 0 0
ENTERA BIO LTD SHS M40527109 6,624 2,353,000 SH   SOLE   2,353,000 0 0
EYEPOINT PHARMACEUTICALS COM NEW 30233G209 41,255 3,370,506 SH   SOLE   3,370,506 0 0
FORMA THERAPEUTICS SHS 34633R104 128,146 9,011,651 SH   SOLE   9,011,651 0 0
FRAZIER LIFESCIENCES ACQU CO CL A SHS G3710A121 9,920 1,000,000 SH   SOLE   1,000,000 0 0
GERON CORP COM 374163103 36,754 30,126,299 SH   SOLE   30,126,299 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106 66,345 2,843,757 SH   SOLE   2,843,757 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 6,300 625,000 SH   SOLE   625,000 0 0
ICOSAVAX INC COM 45114M109 132,231 5,779,347 SH   SOLE   5,779,347 0 0
IKENA ONCOLOGY INC COM 45175G108 9,405 750,000 SH   SOLE   750,000 0 0
IMMUNOGEN INC COM 45253H101 150,192 20,241,458 SH   SOLE   20,241,458 0 0
INSTIL BIO INC COM 45783C101 83,339 4,870,793 SH   SOLE   4,870,793 0 0
IO BIOTECH INC COM 449778109 11,890 1,857,755 SH   SOLE   1,857,755 0 0
ITEOS THERAPEUTICS INC COM 46565G104 205,668 4,417,259 SH   SOLE   4,417,259 0 0
JANUX THERAPEUTICS INC COM 47103J105 171,072 8,670,644 SH   SOLE   8,670,644 0 0
KALA PHARMACEUTICALS INC COM 483119103 13,158 10,874,613 SH   SOLE   10,874,613 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 25,538 1,930,322 SH   SOLE   1,930,322 0 0
KINNATE BIOPHARMA INC COM 49705R105 63,669 3,593,052 SH   SOLE   3,593,052 0 0
LARIMAR THERAPEUTICS INC COM 517125100 14,400 1,334,610 SH   SOLE   1,334,610 0 0
LIANBIO SPONSORED ADS 53000N108 47,155 7,655,015 SH   SOLE   7,655,015 0 0
MACROGENICS INC COM 556099109 97,963 6,103,594 SH   SOLE   6,103,594 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 14,715 2,246,503 SH   SOLE   2,246,503 0 0
MIRATI THERAPEUTICS INC COM 60468T105 55,896 381,046 SH   SOLE   381,046 0 0
NAUTILUS COM 63909J108 12,621 2,436,430 SH   SOLE   2,436,430 0 0
NKARTA INC COM 65487U108 86,039 5,605,129 SH   SOLE   5,605,129 0 0
NOVAVAX INC COM NEW 670002401 300,131 2,097,794 SH   SOLE   2,097,794 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106 20,128 2,150,404 SH   SOLE   2,150,404 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 12,797 9,694,789 SH   SOLE   9,694,789 0 0
OTONOMY INC COM 68906L105 11,648 5,600,000 SH   SOLE   5,600,000 0 0
PARDES BIOSCIENCES INC Com 69945Q105 51,190 3,127,038 SH   SOLE   3,127,038 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 7,439 2,850,000 SH   SOLE   2,850,000 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 61,272 3,115,008 SH   SOLE   3,115,008 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 39,507 1,710,265 SH   SOLE   1,710,265 0 0
POINT BIOPHARMA GLOBAL INC COM 730541109 50,417 9,003,018 SH   SOLE   9,003,018 0 0
PYXIS ONCOLOGY INC COMMON STOCK 747324101 25,035 2,282,173 SH   SOLE   2,282,173 0 0
RELAY THERAPEUTICS INC COM 75943R102 16,861 549,055 SH   SOLE   549,055 0 0
RELMADA THERAPEUTICS COM 75955J402 45,060 2,000,000 SH   SOLE   2,000,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 45,999 2,107,149 SH   SOLE   2,107,149 0 0
RXSIGHT INC COM 78349D107 34,344 3,052,796 SH   SOLE   3,052,796 0 0
SATSUMA PHARMACEUTICALS INC COM 80405P107 26,614 5,914,252 SH   SOLE   5,914,252 0 0
SCPHARMACEUTICALS COM 810648105 13,513 2,691,770 SH   SOLE   2,691,770 0 0
SILVERBACK THERAPEUTICS INC COM 82835W108 11,603 1,742,186 SH   SOLE   1,742,186 0 0
SOLID BIOSCIENCES INC COM 83422E105 21,644 12,367,873 SH   SOLE   12,367,873 0 0
SYNLOGIC INC COM 87166L100 16,133 6,666,666 SH   SOLE   6,666,666 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 2,934 900,000 SH   SOLE   900,000 0 0
TANGO THERAPEUTICS INC COM 87583X109 24,615 2,250,000 SH   SOLE   2,250,000 0 0
TENAYA THERAPEUTICS INC COM 87990A106 67,301 3,551,508 SH   SOLE   3,551,508 0 0
TG THERAPEUTICS INC COM 88322Q108 41,993 2,210,145 SH   SOLE   2,210,145 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 174,272 5,614,428 SH   SOLE   5,614,428 0 0
TSCAN THERAPEUTICS INC COM 89854M101 5,649 1,255,317 SH   SOLE   1,255,317 0 0
TYRA BIOSCIENCES INC COM 90240B106 101,817 7,236,454 SH   SOLE   7,236,454 0 0
VAXCYTE INC COM 92243G108 100,881 4,240,464 SH   SOLE   4,240,464 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 34,272 5,100,000 SH   SOLE   5,100,000 0 0
VOR BIOPHARMA INC COM 929033108 129,226 11,120,973 SH   SOLE   11,120,973 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 24,414 7,775,207 SH   SOLE   7,775,207 0 0
WEREWOLF THERAPEUTICS INC COM 95075A107 51,116 4,291,881 SH   SOLE   4,291,881 0 0
XILIO THERAPEUTICS INC COM 98422T100 32,035 2,002,217 SH   SOLE   2,002,217 0 0
ZOGENIX INC COM NEW 98978L204 54,173 3,333,700 SH   SOLE   3,333,700 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 10,069 423,616 SH   SOLE   423,616 0 0
CVRX INC COM 126638105 3,363 275,000 SH   SOLE   275,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 69,737 1,804,795 SH   SOLE   1,804,795 0 0
CHINOOK THERAPEUTICS COM 16961L106 16,310 1,000,000 SH   SOLE   1,000,000 0 0
GRAPHITE BIO INC COM 38870X104 33,541 2,698,369 SH   SOLE   2,698,369 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 48,613 4,871,067 SH   SOLE   4,871,067 0 0
VERVE THERAPEUTICS INC COM 92539P101 11,440 310,284 SH   SOLE   310,284 0 0