<SEC-DOCUMENT>0001104659-22-022781-index.html : 20220214
<SEC-HEADER>0001104659-22-022781.hdr.sgml : 20220214
<ACCEPTANCE-DATETIME>20220214161150
ACCESSION NUMBER:		0001104659-22-022781
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20220214
DATE AS OF CHANGE:		20220214
GROUP MEMBERS:		PETER KOLCHINSKY
GROUP MEMBERS:		RA CAPITAL HEALTHCARE FUND, L.P.
GROUP MEMBERS:		RAJEEV SHAH

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Milestone Pharmaceuticals Inc.
		CENTRAL INDEX KEY:			0001408443
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			A8
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91001
		FILM NUMBER:		22631926

	BUSINESS ADDRESS:	
		STREET 1:		1111 BOUL. DR.-FREDERIK-PHILIPS, STE 420
		CITY:			MONTREAL
		STATE:			A8
		ZIP:			H4M 2X6
		BUSINESS PHONE:		(514) 336-0444

	MAIL ADDRESS:	
		STREET 1:		1111 BOUL. DR.-FREDERIK-PHILIPS, STE 420
		CITY:			MONTREAL
		STATE:			A8
		ZIP:			H4M 2X6

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RA CAPITAL MANAGEMENT, L.P.
		CENTRAL INDEX KEY:			0001346824
		IRS NUMBER:				830406777
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		200 BERKELEY STREET, 18TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		617-778-2500

	MAIL ADDRESS:	
		STREET 1:		200 BERKELEY STREET, 18TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	RA CAPITAL MANAGEMENT, LLC
		DATE OF NAME CHANGE:	20051213
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>tm225316-39_sc13ga.htm
<DESCRIPTION>SC 13G/A
<TEXT>
Document 1 - file: tm225316-39_sc13ga.htm

</DOCUMENT>
</SEC-DOCUMENT>