0001104659-21-024161.txt : 20210216 0001104659-21-024161.hdr.sgml : 20210216 20210216163214 ACCESSION NUMBER: 0001104659-21-024161 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20201231 FILED AS OF DATE: 20210216 DATE AS OF CHANGE: 20210216 EFFECTIVENESS DATE: 20210216 FILER: COMPANY DATA: COMPANY CONFORMED NAME: RA CAPITAL MANAGEMENT, L.P. CENTRAL INDEX KEY: 0001346824 IRS NUMBER: 830406777 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-12884 FILM NUMBER: 21639332 BUSINESS ADDRESS: STREET 1: 200 BERKELEY STREET, 18TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 617-778-2500 MAIL ADDRESS: STREET 1: 200 BERKELEY STREET, 18TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 FORMER COMPANY: FORMER CONFORMED NAME: RA CAPITAL MANAGEMENT, LLC DATE OF NAME CHANGE: 20051213 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001346824 XXXXXXXX 12-31-2020 12-31-2020 false RA CAPITAL MANAGEMENT, L.P.

200 BERKELEY STREET, 18TH FLOOR Boston MA 02116

13F HOLDINGS REPORT 028-12884 N Rajeev Shah 617-778-2500 /s/ Rajeev Shah Boston MA 02-16-2021 0 82 7153595 INFORMATION TABLE 2 infotable.xml ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 13470 2499025 SH SOLE 2499025 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 103006 9502383 SH SOLE 9502383 0 0 AKOUOS INC COM 00973J101 45237 2281249 SH SOLE 2281249 0 0 ALECTOR INC COM 014442107 24463 1616879 SH SOLE 1616879 0 0 ARDELYX INC COM 039697107 39875 6163086 SH SOLE 6163086 0 0 ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 32777 1165184 SH SOLE 1165184 0 0 ARVINAS INC COM 04335A105 311937 3672872 SH SOLE 3672872 0 0 ARYA SCIENCES ACQUISITION CO COM CL A G3166W106 10850 1000000 SH SOLE 1000000 0 0 ASCENDIS PHARMA A S SPONSORED ADR 04351P101 978221 5865338 SH SOLE 5865338 0 0 ATEA PHARMACEUTICALS INC COM 04683R106 224294 5368451 SH SOLE 5368451 0 0 AXSOME THERAPEUTICS INC COM 05464T104 134869 1655447 SH SOLE 1655447 0 0 BCTG ACQUISITION CORP COM 05492W103 14300 1250000 SH SOLE 1250000 0 0 BLACK DIAMOND THERAPEUTICS INC COM 09203E105 83006 2589904 SH SOLE 2589904 0 0 BCLS ACQUISITION CORP COM CL A G0904B105 13925 1250000 SH SOLE 1250000 0 0 C4 THERAPEUTICS INC COM STK 12529R107 45639 1377569 SH SOLE 1377569 0 0 CHEMOCENTRYX INC COM 16383L106 295764 4776548 SH SOLE 4776548 0 0 CEREVEL THERAPEUTICS HLDNG INC COM 15678U128 36476 2200000 SH SOLE 2200000 0 0 CEREVEL THERAPEUTICS HLDNG INC *W EXP 06/09/2027 15678U102 1318 233333 SH SOLE 233333 0 0 CONCERT PHARMACEUTICALS INC COM 206022105 23049 1823520 SH SOLE 1823520 0 0 CONSTELLATION PHARMCETICLS INC COM 210373106 53359 1852746 SH SOLE 1852746 0 0 COGENT BIOSCIENCES INC COM 19240Q201 11518 1025641 SH SOLE 1025641 0 0 CARDIFF ONCOLOGY INC COM 14147L108 59187 3290000 SH SOLE 3290000 0 0 CURIS INC COM NEW 231269200 63127 7707790 SH SOLE 7707790 0 0 CRINETICS PHARMACEUTICALS INC COM 22663K107 7959 564102 SH SOLE 564102 0 0 DYNE THERAPEUTICS INC COM 26818M108 58906 2805045 SH SOLE 2805045 0 0 89BIO INC COM 282559103 115422 4736214 SH SOLE 4736214 0 0 FRAZIER LIFESCIENCES ACQUISITION CO UNIT 12/09/2025 G3710A121 10380 1000000 SH SOLE 1000000 0 0 FORMA THERAPEUTICS HLDGS INC SHS 34633R104 314507 9011651 SH SOLE 9011651 0 0 FIVE PRIME THERAPEUTICS INC COM 33830X104 72891 4285161 SH SOLE 4285161 0 0 5 01 ACQUISITION CORP COM CL A 33836P105 7628 750000 SH SOLE 750000 0 0 GERON CORP COM 374163103 47901 30126299 SH SOLE 30126299 0 0 HELIX ACQUISITION CORP COM CL A G4444C102 7959 700000 SH SOLE 700000 0 0 HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 8006 625000 SH SOLE 625000 0 0 IGM BIOSCIENCES INC COM 449585108 86765 982723 SH SOLE 982723 0 0 IMARA INC COM 45249V107 5486 248804 SH SOLE 248804 0 0 IMMUNOGEN INC COM 45253H101 118793 18417458 SH SOLE 18417458 0 0 INHIBRX INC COM 45720L107 70193 2129003 SH SOLE 2129003 0 0 INOZYME PHARMA INC COM 45790W108 41355 2003653 SH SOLE 2003653 0 0 ITEOS THERAPEUTICS INC COM 46565G104 149392 4417258 SH SOLE 4417258 0 0 KALA PHARMACEUTICALS INC COM 483119103 73730 10874613 SH SOLE 10874613 0 0 KINNATE BIOPHARMA INC COM 49705R105 142932 3593052 SH SOLE 3593052 0 0 KEROS THERAPEUTICS INC COM 492327101 132263 1875000 SH SOLE 1875000 0 0 LEGEND BIOTECH CORP SPONSORED ADS 52490G102 67818 2408292 SH SOLE 2408292 0 0 LYRA THERAPEUTICS INC COM 55234L105 9301 815849 SH SOLE 815849 0 0 LARIMAR THERAPEUTICS INC COM 517125100 32439 1515151 SH SOLE 1515151 0 0 MIRAGEN THERAPEUTICS INC COM NEW 60463E202 7434 451932 SH SOLE 451932 0 0 MACROGENICS INC COM 556099109 100017 4375217 SH SOLE 4375217 0 0 MILESTONE PHARMACEUTICALS INC COM 59935V107 15596 2327714 SH SOLE 2327714 0 0 MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 15860 1300000 SH SOLE 1300000 0 0 NKARTA INC COM 65487U108 344547 5605129 SH SOLE 5605129 0 0 NOVAVAX INC COM NEW 670002401 422463 3788564 SH SOLE 3788564 0 0 OCULAR THERAPEUTIX INC COM 67576A100 15525 750000 SH SOLE 750000 0 0 OLEMA PHARMACEUTICALS INC COM 68062P106 103391 2150404 SH SOLE 2150404 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 19768 584000 SH SOLE 584000 0 0 ORCHARD THERAPEUTICS PLC ADS 68570P101 41155 12315213 SH SOLE 12315213 0 0 OVID THERAPEUTICS INC COM 690469101 658 285000 SH SOLE 285000 0 0 PACIFIC BIOSCIENCES OF CALIFORNIA INC COM 69404D108 51569 1987997 SH SOLE 1987997 0 0 PANDION THERAPEUTICS INC COM 698340106 26285 1770023 SH SOLE 1770023 0 0 PASSAGE BIO INC COM 702712100 8250 322630 SH SOLE 322630 0 0 VAXCYTE INC COM 92243G108 98593 3710699 SH SOLE 3710699 0 0 PHATHOM PHARMACEUTICALS INC COM 71722W107 127067 3825008 SH SOLE 3825008 0 0 PMV PHARMACEUTICALS INC COM 69353Y103 105198 1710265 SH SOLE 1710265 0 0 PROFOUND MEDICAL CORP COM NEW 74319B502 3954 192311 SH SOLE 192311 0 0 ROCKET PHARMACEUTICALS INC COM COM 77313F106 117143 2136081 SH SOLE 2136081 0 0 RELAY THERAPEUTICS INC COM 75943R102 41560 1000000 SH SOLE 1000000 0 0 REPARE THERAPEUTICS INC COM 760273102 14029 409000 SH SOLE 409000 0 0 RHYTHM PHARMACEUTICALS INC COM 76243J105 124244 4179067 SH SOLE 4179067 0 0 SILVERBACK THERAPEUTICS INC COM 82835W108 80733 1742186 SH SOLE 1742186 0 0 SCPHARMACEUTICALS INC COM 810648105 18615 3518998 SH SOLE 3518998 0 0 SOLID BIOSCIENCES INC COM 83422E105 75622 9976569 SH SOLE 9976569 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 22753 1023067 SH SOLE 1023067 0 0 SUTRO BIOPHARMA INC COM 869367102 45986 2118212 SH SOLE 2118212 0 0 SATSUMA PHARMACEUTICALS INC COM 80405P107 21583 4681858 SH SOLE 4681858 0 0 TG THERAPEUTICS INC COM 88322Q108 451818 8685471 SH SOLE 8685471 0 0 TRILLIUM THERAPEUTICS INC COM NEW 89620X506 77823 5290481 SH SOLE 5290481 0 0 TRAVERE THERAPEUTICS INC COM 89422G107 124225 4557867 SH SOLE 4557867 0 0 THERAPEUTICSMD INC COM 88338N107 9453 7812500 SH SOLE 7812500 0 0 VERONA PHARMA PLC SPONSORED ADS 925050106 31824 5100000 SH SOLE 5100000 0 0 VAXART INC COM NEW 92243A200 15658 2742271 SH SOLE 2742271 0 0 WAVE LIFE SCIENCES LTD SHS Y95308105 61191 7775207 SH SOLE 7775207 0 0 X4 PHARMACEUTICALS INC COM 98420X103 3453 536962 SH SOLE 536962 0 0 ZOGENIX INC COM NEW 98978L204 106859 5345631 SH SOLE 5345631 0 0