UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

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☐	Soliciting Material Pursuant to § 240.14a-12

Xeris Pharmaceuticals, Inc.

(Name of Registrant as Specified in its Charter)

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September 16, 2020

Dear Stockholder:

We have previously sent to you proxy material for the Special Meeting of Stockholders of Xeris Pharmaceuticals, Inc. to be held on October 8, 2020. Your Board of Directors unanimously recommends that stockholders vote FOR approval of a stock option exchange program for certain eligible employees and consultants who are not executive officers.

Your vote is important, no matter how many or how few shares you may own. If you have not already done so, please vote TODAY by telephone, via the Internet, or by signing, dating and returning the enclosed proxy card in the envelope provided.

Very truly yours,

Paul R. Edick

Chairman and Chief Executive Officer

REMEMBER:

You can vote your shares by telephone, or via the Internet.

Please follow the easy instructions on the enclosed proxy card.

If you have any questions, or need assistance in voting

your shares, please call our proxy solicitor,

INNISFREE M&A INCORPORATED

TOLL-FREE, at 1 (888) 750-5834.