X0306 4/A 2019-07-01 2019-07-03 0 0001346302 XERIS PHARMACEUTICALS INC XERS 0001652410 Hecht Beth C/O XERIS PHARMACEUTICALS, INC. 180 N. LASALLE STREET, SUITE 1600 CHICAGO IL 60601 0 1 0 0 See Remarks Common Stock 3624 D On July 3, 2019, the reporting person filed a Form 4 which inadvertently reported that, following her purchase of the underlying stock, she directly owned 3,928 shares of the issuer's common stock. In fact, as reported in this amendment, the reporting person directly owned 3,624 shares of common stock. Senior Vice President, General Counsel and Corporate Secretary /s/ Beth Hecht 2019-09-12