Condensed Consolidated Statements of Loss and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Revenue
Collaboration revenue	$ 720	$ 618
Product sales	0	87
Total revenues	720	705
Cost of goods sold	945	6,147
Research and development	2,438	3,824
General and administrative	2,392	3,737
Total operating expenses	5,775	13,708
Loss from operations	(5,055)	(13,003)
Change in fair value of contingent consideration liability	200	14,833
Gain on restructuring of financing obligations	2,506	0
Gain on fair value of inventory received resulting from restructuring of financing obligations	945	0
Interest and other income/expense, net	2	(5)
Interest expense	(1,960)	(2,229)
Net loss	$ (3,362)	$ (404)
Net loss per share - basic and diluted	$ (0.16)	$ (0.02)
Shares used to compute net loss per share - basic and diluted	20,807	19,750
Other Comprehensive Loss
Change in unrealized (loss) income on marketable securities	$ 0	$ 2
Comprehensive loss	$ (3,362)	$ (402)