X0303 4 2010-02-23 0 0000319240 IRIS INTERNATIONAL INC IRIS 0001343621 Yi John U C/O IRIS INTERNATIONAL, INC. 9172 ETON AVENUE CHATSWORTH CA 91311 0 1 0 0 Corp VP, Operations Stock Option (Right to Buy) 11.97 2010-02-23 4 A 0 22684 0 A 2017-02-23 Common Stock 22684 22684 D Restricted Stock Units 2010-02-23 4 A 0 3342 0 A Common Stock 3342 3342 D Vests 25% on February 23, 2011 and thereafter 6.25% will vest in 12 equal quarterly installments with the first such installment vesting on June 30, 2011. Each restricted stock unit represents a contingent right to receive one share of IRIS International, Inc. common stock. Vests 25% on March 23, 2011 and thereafter 6.25% will vest in 12 equal quarterly installments with the first such installment vesting on June 30, 2011. Vested shares will be delivered to the reporting person as soon as practicable following the applicable vesting date. /s/ Todd M. Graham, Attorney-In-Fact 2010-02-25