X0304 4 2012-03-02 0 0001492426 HORIZON PHARMA, INC. HZNP 0001342821 Himawan Jeff 21 WATERWAY SUITE 225 THE WOODLANDS TX 77380 1 0 1 0 Common Stock 2012-03-02 4 P 0 2761477 3.59 A 5064731 I See Footnote Warrant to Purchase Common Stock 4.308 2012-03-02 4 C 0 690369 0.0313 A 2012-03-02 2017-03-02 Common Stock 690369 690369 I See Footnote The securities are held directly by Essex Woodlands Health Ventures Fund VII, L.P. (the "Fund"). The Reporting Person is a manager of Essex Woodlands Health Ventures VII, LLC, which is the general partner of Essex Woodlands Health Ventures VII, L.P., the general partner of the Fund. The Reporting Person disclaims beneficial ownership of the reported securities, except to the extent of his pecuniary interest therein. /s/ Jeff Himawan 2012-03-05