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Statements of Cash Flows - USD ($)
6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (17,447,496) $ (10,399,881)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 1,853,199 1,463,330
Amortization of debt discount - non-cash interest expense 7,738 10,392
Net amortization of premium on debt securities available for sale 7,163 130,362
Depreciation 29,282 19,963
Change in assets and liabilities:    
Prepaid expenses and other current assets (373,938) (302,801)
Accounts payable (198,838) 487,240
Accrued expenses 1,922,606 (907,346)
Net cash used in operating activities (14,200,284) (9,498,741)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Acquisitions of property and equipment (200,763) (11,592)
Purchases of marketable securities (12,091,149) (9,270,343)
Sales of marketable securities 17,950,000 10,822,000
Net cash provided by investing activities 5,658,088 1,540,065
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from issuance of common stock, net of issuance costs 13,124,533 10,585,744
Proceeds from issuance of common stock in Employee Stock Purchase Plan   45,555
Deferred offering costs paid in cash   (77,942)
Net cash provided by financing activities 13,124,533 10,553,357
NET CHANGE IN CASH AND CASH EQUIVALENTS 4,582,337 2,594,681
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD 20,023,337 12,015,061
CASH AND CASH EQUIVALENTS, END OF PERIOD 24,605,674 14,609,742
Cash paid during the period for:    
Interest $ 46,877 $ 41,642