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        <issuerName>Molecular Insight Pharmaceuticals, Inc.</issuerName>
        <issuerTradingSymbol>MIPI</issuerTradingSymbol>
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            <rptOwnerName>Barlow David S</rptOwnerName>
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            <rptOwnerState>MA</rptOwnerState>
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    <ownerSignature>
        <signatureName>MR. WILLIAM F. RUCCI JR., CPA, MST, AS ATTORNEY-IN-FACT FOR DAVID S. BARLOW</signatureName>
        <signatureDate>2009-01-21</signatureDate>
    </ownerSignature>
</ownershipDocument>
