X0202 4 2007-06-26 0 0001340752 Molecular Insight Pharmaceuticals, Inc. MIPI 0001204788 STACK DAVID M MOLECULAR INSIGHT PHARMACEUTICALS, INC. 160 SECOND STREET CAMBRIDGE MA 02142 1 0 0 0 Stock Option (right to buy) 12.16 2007-06-26 4 A 0 25000 0.00 A 2008-05-15 Common Stock, par value $0.01 per share 25000 25000 D The Amended and Restated 2006 Equity Incentive Plan of the Issuer provided for an option grant on May 15, 2007 to the reporting person. This grant was reviewed and affirmed by the Compensation Committee of the Issuer's Board of Directors on June 26, 2007. This option terminates on the earlier of (i) May 15, 2017 and (ii) ninety (90) days afer the reporting person ceases to be a director of the Issuer. /s/ Adria E. Warren, Esq., as Attorney-in-Fact for David M. Stack 2007-06-28