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    <periodOfReport>2022-01-01</periodOfReport>

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    <issuer>
        <issuerCik>0001340652</issuerCik>
        <issuerName>ChemoCentryx, Inc.</issuerName>
        <issuerTradingSymbol>CCXI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001423084</rptOwnerCik>
            <rptOwnerName>Schall Thomas J.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O CHEMOCENTRYX, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>835 INDUSTRIAL ROAD, SUITE 600</rptOwnerStreet2>
            <rptOwnerCity>SAN CARLOS</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94070</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President and CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

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            </transactionDate>
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    <footnotes>
        <footnote id="F1">Shares were acquired upon vesting of restricted stock units awarded on March 4, 2019.</footnote>
        <footnote id="F2">Shares were acquired upon vesting of restricted stock units awarded on March 3, 2020.</footnote>
        <footnote id="F3">Shares were acquired upon vesting of restricted stock units awarded on February 25, 2021.</footnote>
        <footnote id="F4">Represents shares withheld upon vesting of restricted stock units to satisfy tax withholding obligation.</footnote>
        <footnote id="F5">Each restricted stock unit represents a contingent right to receive one share of CCXI common stock.</footnote>
        <footnote id="F6">The restricted stock units awarded on March 4, 2019, vest in three equal installments on January 1, 2020, January 1, 2021, and January 1, 2022, subject to the Reporting Person's continued service to the Company on such date.  Shares will be delivered to the Reporting Person within thirty (30) days following vest date.</footnote>
        <footnote id="F7">The restricted stock units awarded on March 3, 2020, vest in three equal installments on January 1, 2021, January 1, 2022, and January 1, 2023, subject to the Reporting Person's continued service to the Company on such date.  Shares will be delivered to the Reporting Person within thirty (30) days following vest date.</footnote>
        <footnote id="F8">The restricted stock units awarded on February 25, 2021, vests in three equal installments on January 1, 2022, January 1, 2023, and January 1, 2024, subject to the Reporting Person's continued service to the Company on such date.  Shares will be delivered to the Reporting Person within thirty (30) days following vest date.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Susan M. Kanaya, as Attorney-in-Fact</signatureName>
        <signatureDate>2022-01-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
