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Accrued and Other Current Liabilities (Detail) - USD ($)
$ in Thousands
Jun. 30, 2022
Dec. 31, 2021
Payables and Accruals [Abstract]    
Research and development related $ 9,539 $ 11,309
Compensation related 6,737 8,350
Consulting and professional services 1,329 1,348
Current portion of operating lease liability [1] $ 3,035 $ 2,810
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Accrued liabilities Accrued liabilities
End of term charge on the long-term debt $ 1,196 $ 1,151
Commercial manufacturing related 3,013
Other 2,895 1,390
Accrued liabilities $ 27,744 $ 26,358
[1] Includes current portion of operating lease liabilities.