Related-Party Transactions - Additional Information (Detail) - USD ($)		1 Months Ended							3 Months Ended			12 Months Ended
	Dec. 28, 2017	Jan. 31, 2022	Sep. 30, 2021	Feb. 28, 2021	Jun. 30, 2018	Dec. 31, 2017	Feb. 28, 2017	May 31, 2016	Mar. 31, 2022	Mar. 31, 2021	Jun. 30, 2020	Dec. 31, 2021	Dec. 31, 2017	May 09, 2016
Related Party Transaction [Line Items]
Non refundable upfront payments received								$ 85,000,000.0
Non refundable upfront payment received in equity investment, shares								3,333,333
Performance obligations satisfied (or partially satisfied) in previous periods									$ 2,254,000	$ 8,443,000
Transaction price														$ 78,000,000.0
Upfront payments received								$ 78,000,000.0
Non refundable upfront payments allocated for issuance of common stock								$ 7,000,000.0
Issuance of common stock, per share value								$ 2.10
Collaboration and license revenue from related party									106,000	10,223,000
Avacopan Agreement [Member]
Related Party Transaction [Line Items]
Non refundable upfront payments received							$ 20,000,000.0	$ 85,000,000.0
Non refundable upfront payment received in cash								60,000,000.0
Non refundable upfront payment received in equity investment								$ 25,000,000.0
Share price of common stock in equity investment								$ 7.50
Non refundable upfront payment received in equity investment, shares								3,333,333
Non refundable payment for expanded rights					$ 5,000,000.0
Performance obligations satisfied (or partially satisfied) in previous periods						$ 50,000,000.0
Transaction price									228,000,000.0
Collaboration and license revenue from related party									100,000	9,900,000
Avacopan Amendment [Member]
Related Party Transaction [Line Items]
Upfront cash commitment							$ 20,000,000.0
Avacopan Letter Agreement [Member]
Related Party Transaction [Line Items]
Non refundable payment for expanded rights	$ 5,000.0
Revenues recognized									6,200,000
Avacopan Letter Agreement [Member] | Maximum [Member]
Related Party Transaction [Line Items]
Potential milestone payments receivable									385,000,000.0
CCX140 Agreement [Member]
Related Party Transaction [Line Items]
Non refundable payment for expanded rights					5,000,000.0				5,000,000.0				$ 50,000,000.0
Transaction price									66,500,000
Upfront payments received									50,000,000.0
Collaboration and license revenue from related party									0	$ 300,000
Non refundable upfront commitment					$ 11,500,000
Deferred Revenue, Recognized											$ 46,700,000
Other current liabilities to related party									$ 6,200,000
Development Funding, Reduction											$ 47,200,000
Tavneos [Member]
Related Party Transaction [Line Items]
Performance obligations satisfied (or partially satisfied) in previous periods		$ 45,000,000.0	$ 20,000,000.0	$ 10,000,000.0								$ 30,000,000.0
Vifor [Member]
Related Party Transaction [Line Items]
Purchase of Common stock, shares									5,194,085
Non refundable payment for expanded rights		$ 45,000,000.0
Vifor [Member] | CCX140 Agreement [Member]
Related Party Transaction [Line Items]
Development funding									$ 11,500,000