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Income Taxes - Reconciliation of the Federal Statutory Income Tax Rate to the Company's Effective Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Income Tax Disclosure [Abstract]      
Federal statutory income tax rate (21.00%) (21.00%) (21.00%)
State, net of federal benefit (0.40%) 0.00% 0.00%
Permanent items 1.20% 2.10% 1.30%
Excess tax benefit for stock-based compensation (3.00%) (40.90%) (13.30%)
Tax credits 3.10% 13.40% 38.30%
Change in valuation allowance 22.90% 70.40% 70.30%
Non-deductible executive compensation 3.30% 2.70% 1.00%
Other 0.10% 0.10% 0.00%
(Benefit from) provision for income taxes 0.00% 0.00% 0.00%