Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Revenue:
Product sales, net	$ 965	$ 0	$ 0
Product supply sales to related party	1,836	0	0
Collaboration and license revenue from related party	29,099	64,392	35,952
Grant revenue	324	499	176
Total revenue	32,224	64,891	36,128
Operating expenses:
Cost of sales	302	0	0
Research and development	82,990	77,882	70,276
Selling, general and administrative	78,851	42,186	24,155
Total operating expenses	162,143	120,068	94,431
Loss from operations	(129,919)	(55,177)	(58,303)
Other income (expense):
Interest income	859	2,464	4,963
Interest expense	(2,695)	(2,643)	(2,149)
Total other income (expense), net	(1,836)	(179)	2,814
Net loss	$ (131,755)	$ (55,356)	$ (55,489)
Net loss per common share
Basic and diluted net loss per common share	$ (1.89)	$ (0.84)	$ (0.98)
Shares used to compute basic and diluted net loss per common share	69,851	65,688	56,898