X0101 EFFECT 33 LIVE 2010-08-20 16:30:00

S-4

0001340282 Rosetta Resources Inc. 333-168225 0001463588 Rosetta Resources Offshore, LLC 333-168225-05 0001463586 Rosetta Resources Holdings, LLC 333-168225-04 0001463587 Rosetta Resources Operating GP, LLC 333-168225-03 0001463585 Rosetta Resources Operating LP 333-168225-02 0001463584 Rosetta Resources Gathering LP 333-168225-01