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Consolidated Statement of Cash Flows - EUR (€)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Operating Activities:      
Consolidated Net Profit / (Loss) € (189,734,199) € (151,058,190) € (514,460,016)
Adjustments to Reconcile Consolidated Net Profit / (Loss) to Net Cash Provided by / (Used in) Operating Activities:      
Impairments of Assets 22,276,282 7,805,764 235,916,060
Depreciation and Amortization of Tangible and Intangible Assets and of Right-of-Use Assets 10,535,352 10,535,414 10,090,958
Net (Gain) / Loss of Other Financial Assets (24,502,933) (3,205,253) (3,376,711)
(Income) from Reversals of Impairments / Impairments on Financial Assets (468,180) 12,000 (316,000)
Net (Gain) / Loss on Derivative Financial Instruments 50,028 (212,445) 3,495,651
Non Cash Effective Net Change in Financial Assets / Liabilities from Collaborations (106,731,155) (301,066,774) (16,007,722)
Non Cash Effective Net Change in Financial Liabilities from Future Payments to Royalty Pharma (45,666,089) (46,764,425) 42,766,283
Gain on Repurchase and interest expense from Convertible Bond (5,340,499) 12,502,457 12,055,784
Share-based Payment 27,370,992 3,638,977 2,585,426
Non Cash Income from Capitalization of Investment in Associates 0 (19,874,779) 0
Cash Income from Sales of Shares of Investment in Associates (4,238,556) 0 0
Share of Loss of Associates accounted for using the Equity Method 8,174,607 4,305,026 0
Change in Fair Value Anti-Dilution Asset 4,253,268 0 0
Other Cash and Non-Cash Expenses (+) / Income (-) 3,798,704 0 0
Income Tax (Benefit) / Expenses (1,188,537) 168,578,523 (76,590,860)
Changes in Operating Assets and Liabilities:      
Accounts Receivable 56,874,720 (18,165,270) 10,532,824
Income Tax Receivables, Other Receivables, Inventories and Prepaid Expenses and Other Assets (24,828,127) (11,924,577) (30,348,390)
Accounts Payable and Accruals, Lease Liabilities, Tax Liabilities and Provisions (44,276,990) (21,092,954) (90,815,610)
Contract Liability 19,443,663 (252,594) (2,363,139)
Income Taxes Paid (-) / Received (+) (1,639,294) (466,161) (64,609,622)
Net Cash Provided by / (Used in) Operating Activities (295,836,943) (366,705,261) (481,445,084)
Investing Activities:      
Cash Payments to Acquire Other Financial Assets (3,151,166,904) (1,884,857,008) (2,188,341,595)
Cash Receipts from Sales of Other Financial Assets 3,142,300,000 2,240,651,170 2,591,975,683
Cash Payments for Derivative Financial Instruments (50,028) 0 (3,495,651)
Cash Receipts from Derivative Financial Instruments 0 212,445 0
Acquisitions, Net of Cash Acquired 0 0 (1,206,609,948)
Cash Payments to Acquire Property, Plant and Equipment (349,467) (1,932,486) (3,810,210)
Cash Receipts from Sales of Property, Plant and Equipment 0 0 0
Cash Payments to Acquire Intangible Assets (2,523,224) (13,296,176) (22,345,955)
Cash Receipts from Sales of Shares at Fair Value through Other Comprehensive Income 4,360,421 0 0
Cash Income from Sales of Shares of Investment in Associates 4,578,999 0 0
Cash Receipts from Sales of Subsidiaries 0 0 0
Interest Received 18,224,464 4,225,330 1,617,544
Net Cash Provided by / (Used in) Investing Activities 15,374,261 345,003,275 (831,010,132)
Financing Activities:      
Cash Proceeds from Issuing Shares 102,695,820 0 84,730,022
Cash Payments for Costs from Issuing Shares (6,650,567) 0 (91,417)
Cash Proceeds in Connection with Exercised Stock (2021) and Convertible Bonds (2020) 0 0 241,234
Cash Payments for Repurchases of own Convertible Bonds (40,256,000) 0 0
Payment for transaction costs for repurchases of own convertible bonds (548,856) 0 0
Cash Receipts (+) / Cash Payments (-) from Financing from Collaborations (2,382,119)    
Cash Receipts (+) / Cash Payments (-) from Financing from Collaborations   23,774,611 40,004,094
Cash Receipts from Contracts with Royalty Pharma 0 295,420,975 1,206,706,749
Cash Payments for Costs in Connection with Contracts with Royalty Pharma 0 0 (796,003)
Cash Payments for Principal Elements of Lease Payments (8,023,378) (3,412,760) (3,126,348)
Interest Paid (1,836,396) (4,365,151) (4,744,851)
Net Cash Provided by / (Used in) Financing Activities 42,998,504 311,417,675 1,322,923,480
Effect of Exchange Rate Differences on Cash (6,387,075) (10,613,041) 2,985,312
Increase / (Decrease) in Cash and Cash Equivalents (243,851,253) 279,102,648 13,453,576
Cash and Cash Equivalents at the Beginning of the Period 402,350,904 123,248,256 109,794,680
Cash and Cash Equivalents at the End of the Period € 158,499,651 € 402,350,904 € 123,248,256