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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Cash flows from operating activities:    
Consolidated net loss $ (12,154) $ (7,155)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 81 121
Stock-based compensation 417 360
Amortization of premium of available-for-sale investment securities 237 51
Amortization of right-of-use assets 217 176
Gain on disposal of property and equipment (89)  
Changes in operating assets and liabilities:    
Other receivables 9 1,950
Prepaid expenses and other assets 1,180 395
Accounts payable and accrued expenses 216 (1,521)
Operating lease liability (233) (204)
Net cash used in operating activities (10,119) (5,827)
Cash flows from investing activities:    
Purchases of property and equipment (43) (17)
Purchases of available-for-sale investment securities   (25,678)
Maturities of available-for-sale investment securities 14,500 2,300
Proceeds from sale of property and equipment 169  
Net cash provided by (used in) investing activities 14,626 (23,395)
Cash flows from financing activities:    
Proceeds from issuance of common stock through option exercises 1  
Proceeds from issuance of common stock from at-the-market offerings, net of offering costs 1,480 9,621
Proceeds from issuance of common stock from committed purchase agreement, net of offering costs   15,236
Net cash provided by financing activities 1,481 24,857
Net change in cash and cash equivalents 5,988 (4,365)
Cash and cash equivalents at beginning of period 2,336 16,952
Cash and cash equivalents at the end of period $ 8,324 $ 12,587