Stockholders' Equity - Summary of Stock Option Activity (Detail) - USD ($)	12 Months Ended
Dec. 31, 2021
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Number of Outstanding Options, Beginning Balance	576,534
Number of Outstanding Options, Granted	892,239
Exercises	(10,751)
Number of Outstanding Options, Canceled/forfeited/expired	(45,472)
Number of Outstanding Options, Ending Balance	1,412,550
Number of Outstanding Options, Vested and Expected to Vest, Ending Balance	1,412,550
Number of Outstanding Options, Exercisable, Ending Balance	472,553
Weighted Average Exercise Price, Beginning Balance	$ 23.33
Weighted Average Exercise Price, Granted	5.08
Weighted Average Exercise Price, Exercises	5.78
Weighted Average Exercise Price, Canceled/forfeited/expired	22.38
Weighted Average Exercise Price, Ending Balance	12.01
Weighted Average Exercise Price, Options Vested and Expected to Vest, Ending Balance	12.01
Weighted Average Exercise Price, Options Exercisable, Ending Balance	$ 25.55
Weighted Average Contractual Term, Outstanding	8 years 5 months 15 days
Weighted Average Contractual Term, Options Vested and Expected to Vest	8 years 5 months 15 days
Weighted Average Contractual Term, Options Exercisable	7 years 1 month 6 days
Aggregate Intrinsic Value, Outstanding	$ 3,134,377
Aggregate Intrinsic Value, Options Vested and Expected to Vest	3,134,377
Aggregate Intrinsic Value, Options Exercisable	$ 763,461

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The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

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The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.

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For presentations that combine terminations, the number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan or that expired.

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Weighted average price of options that were either forfeited or expired.

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Gross number of share options (or share units) granted during the period.

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Amount by which the current fair value of the underlying stock exceeds the exercise price of options outstanding.

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Number of options outstanding, including both vested and non-vested options.

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Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

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Amount by which current fair value of underlying stock exceeds exercise price of fully vested and expected to vest options outstanding. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Number of fully vested and expected to vest options outstanding that can be converted into shares under option plan. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Weighted-average exercise price, at which grantee can acquire shares reserved for issuance, for fully vested and expected to vest options outstanding. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Weighted average price at which option holders acquired shares when converting their stock options into shares.

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Weighted average remaining contractual term for vested portions of options outstanding and currently exercisable or convertible, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Weighted average remaining contractual term for fully vested and expected to vest options outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Number of share options (or share units) exercised during the current period.

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