Balance Sheet Details - Summary of Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Property Plant And Equipment [Line Items]
Property and equipment, Gross	$ 6,700	$ 7,523
Less accumulated depreciation and amortization	(6,157)	(6,624)
Property and equipment, Net	543	899
Computer and Office Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, Gross	616	552
Scientific and Laboratory Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, Gross	4,383	5,270
Tenant Improvements [Member]
Property Plant And Equipment [Line Items]
Property and equipment, Gross	$ 1,701	$ 1,701

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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