License, Collaboration and Other Agreements - Additional Information (Detail) - USD ($)	1 Months Ended				12 Months Ended
	Jan. 31, 2021	Jun. 30, 2020	Mar. 31, 2020	Jan. 31, 2020	Dec. 31, 2021	Dec. 31, 2020
Research And Development Arrangement Contract To Perform For Others [Line Items]
Upfront payment received				$ 8,000,000.0
Milestone payments received	$ 2,000,000.0
Other receivables					$ 435,000	$ 2,039,000
Hong Kong University of Science and Technology [Member]
Research And Development Arrangement Contract To Perform For Others [Line Items]
Collaborative agreement, funding received			$ 750,000
Funding of project cost, description			The ITC funded approximately 50% of the total estimated project cost, with aTyr contributing the remaining 50%. The research grant agreement between Pangu BioPharma, HKUST and the Government of the Hong Kong Special Administration Region was effective April 1, 2020.
Expenses					$ 400,000	$ 200,000
Development Regulatory And Sales Milestones [Member] | Kyorin Pharmaceutical Co Ltd [Member]
Research And Development Arrangement Contract To Perform For Others [Line Items]
Remaining receivable based on achievement of research milestones				165,000,000.0
Development Regulatory And Sales Milestones [Member] | Kyorin Pharmaceutical Co Ltd [Member] | Collaboration Revenue [Member]
Research And Development Arrangement Contract To Perform For Others [Line Items]
Stand-alone selling price of license		$ 100,000		$ 7,900,000