X0306 4 2022-11-21 0 0001339970 aTYR PHARMA INC LIFE 0001671026 Shukla Sanjay 3545 JOHN HOPKINS COURT, SUITE #250 SAN DIEGO CA 92121 1 1 0 0 President and CEO Common Stock 2022-11-21 4 P 0 10000 2.1405 A 50798 D Represents weighted average price for the shares. The shares were purchased at prices ranging from $2.13 to $2.16 per share. The reporting person will provide to the Securities and Exchange Commission staff, the issuer, or any security holder of the issuer, upon request, full information regarding the number of shares purchased at each separate price /s/ Nancy E. Denyes, Attorney-in-Fact 2022-11-21