X0306 4 2022-04-26 0 0001339970 aTYR PHARMA INC LIFE 0001219015 CLARKE JOHN K 3545 JOHN HOPKINS COURT, SUITE #250 SAN DIEGO CA 92121 1 0 0 0 Restricted Stock Units 2022-04-26 4 A 0 6000 0.00 A Common Stock 6000 6000 D Each restricted stock unit (RSU) represents a contingent right to receive one share of the Issuer's common stock. The RSUs, granted pursuant to the Issuer's non-employee director compensation policy, vest in full on the earlier of (i) April 26, 2023 or (ii) the Issuer's 2023 Annual Meeting of Stockholders, subject to the Reporting Person's continued service on the Board of Directors. /s/ Nancy E. Denyes, as Attorney-in-Fact 2022-04-28