X0306 4 2020-05-26 0 0001339970 aTYR PHARMA INC LIFE 0001671026 Shukla Sanjay 3545 JOHN HOPKINS COURT, SUITE #250 SAN DIEGO CA 92121 0 1 0 0 President and CEO Employee Stock Option (right to buy) 4.06 2020-05-26 4 A 0 80000 0.00 A 2030-05-26 Common Stock 80000 0 D 50% of the shares subject to this option shall vest and become exercisable in 48 equal monthly installments beginning June 26, 2020, such that these shares will be fully exercisable on May 26, 2024; 25% of the shares subject to this option will vest on May 26, 2021 if and only if a clinical development milestone is achieved by September 30, 2020; and the remaining 25% of the shares will vest on May 26, 2021 if and only if an additional clinical development milestone is achieved by September 30, 2020. Nancy E. Denyes, Attorney-in-Fact 2020-05-28