X0306 4 2019-04-12 0 0001339970 aTYR PHARMA INC LIFE 0001236447 SCHIMMEL PAUL 3545 JOHN HOPKINS COURT, SUITE #250 SAN DIEGO CA 92121 1 0 0 0 Common Stock 40440 D Common Stock 882302 I See Footnote Common Stock 2019-04-12 4 A 0 1848428 0.541 A 2570242 I See Footnote These shares are owned directly by Paul Schimmel Prototype PSP, Paul Schimmel Trustee, FBO Paul Schimmel. The Reporting Person is the sole owner of the Paul Schimmel Prototype PSP, Paul Schimmel Trustee, FBO Paul Schimmel. Represents shares acquired in a registered direct offering pursuant to a Securities Purchase Agreement, dated April 10, 2019, entered between aTyr Pharma, Inc. and the investors named therein. Pursuant to the terms of the Securities Purchase Agreement, investors purchased shares of common stock at a purchase price of $0.541 per share. These shares are owned directly by Schimmel Revocable Trust U/A Dtd 9/6/2000. The Reporting Person and his spouse are trustees of the Schimmel Revocable Trust U/A Dtd 9/6/2000. Nancy D. Krueger, Attorney-in-Fact 2019-04-16