X0306 4 2016-01-27 0 0001339970 aTYR PHARMA INC LIFE 0001640577 Blackburn Stan 3545 JOHN HOPKINS COURT, SUITE 250 SAN DIEGO CA 92121 0 1 0 0 Acting Chief Financial Officer Stock Option (right to buy) 6.14 2016-01-27 4 A 0 4250 0.00 A 2026-01-27 Common Stock 4250 4250 D The shares subject to this option shall vest and become exercisable in 48 equal monthly installments beginning on February 1, 2016, such that this option will be fully exercisable on January 1, 2020. This option is subject to accelerated vesting upon termination without cause upon a change of control of the Issuer. /s/ Nancy Krueger, as Power of Attorney 2016-01-29