X0306 4 2016-01-04 0 0001339970 aTYR PHARMA INC LIFE 0001641093 Ashlock Melissa A. 3545 JOHN HOPKINS COURT, SUITE 250 SAN DIEGO CA 92121 0 1 0 0 See Remarks Employee Stock Option (right to buy) 9.13 2016-01-04 4 A 0 29659 0.00 A Common Stock 29659 29659 D The shares subject to this option shall vest and become exercisable, if at all, in 48 equal monthly installments upon the achievement of certain performance goals, which must be achieved by January 4, 2018, or such option will be subject to immediate forfeiture. This option is subject to accelerated vesting upon termination without cause upon a change of control of the Issuer. SVP, Translational Medicine and Therapeutics /s/ Nancy Krueger, as Power of Attorney 2016-01-06