X0306 4 2015-05-06 0 0001339970 aTYR PHARMA INC LIFE 0001640557 Chrzanowski Holly D. C/O ATYR PHARMA, INC. 3545 JOHN HOPKINS COURT, SUITE #250 SAN DIEGO CA 92121 0 1 0 0 See Remarks Stock Option (right to buy) 14.00 2015-05-06 4 A 0 11943 A 2025-05-06 Common Stock 11943 11943 D The shares subject to this option shall vest and become exercisable in 48 equal monthly installments beginning on May 6, 2015, such that this option is fully exercisable on May 6, 2019. This option is subject to accelerated vesting upon termination without cause upon a change of control of the Issuer. Not applicable. VP, Enterprise Talent and Organization /s/ Nancy Krueger, as Attorney-in-Fact 2015-05-08