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Summary of Significant Accounting Principles - Additional Information (Detail)
12 Months Ended
Dec. 31, 2015
USD ($)
segment
customer
Dec. 31, 2014
USD ($)
customer
Dec. 31, 2013
USD ($)
Dec. 31, 2012
USD ($)
Significant Accounting Policies [Line Items]        
Cash and cash equivalents | $ $ 64,501,000 $ 375,937,000 $ 61,011,000 $ 37,171,000
Maximum days MYALEPT can be held as inventory 21 days      
Amount of material uncertain tax positions | $ $ 0 $ 0    
Number of business segment in which company currently operating | segment 1      
Customer Concentration Risk [Member] | Sales Revenue, Net [Member]        
Significant Accounting Policies [Line Items]        
Number of major customer accounted for net sale and accounts receivable | customer 1 0    
Customer Concentration Risk [Member] | Accounts Receivable [Member]        
Significant Accounting Policies [Line Items]        
Number of major customer accounted for net sale and accounts receivable | customer 1 1    
Accounts receivable, percentage 17.00% 12.00%