X0306 4 2016-01-12 0 0001131324 GENOMIC HEALTH INC GHDX 0001337798 Cole G Bradley 301 PENOBSCOT DRIVE REDWOOD CITY CA 94063 0 1 0 0 COO Common Stock 2016-01-12 4 M 0 542 18.89 A 27970 D Common Stock 2016-01-12 4 M 0 3458 18.89 A 31428 D Common Stock 2016-01-12 4 S 0 542 30.6452 D 30886 D Common Stock 2016-01-12 4 S 0 3458 31.8569 D 27428 D Employee Stock Option (right to buy) 18.89 2016-01-12 4 M 0 542 0.00 D 2016-11-30 Common Stock 542 31458 D Employee Stock Option (right to buy) 18.89 2016-01-12 4 M 0 3458 0.00 D 2016-11-30 Common Stock 3458 28000 D These sales of common stock were effected pursuant to Rule 10b5-1 sales plan adopted by the reporting person on November 24, 2014. Represents weighted average sale price. Actual sale prices ranged from $30.31 to $30.95. Reporting person undertakes to provide upon request by the Securities and Exchange Commission, the issuer or a securityholder of the issuer detailed information regarding the price and number of shares sold within the range indicated. Includes an aggregate of 16,201 shares of common stock issuable pursuant to previously reported restricted stock units and performance-based vesting restricted stock units awards that have not vested. Represents weighted average sale price. Actual sale prices ranged from $31.39 to $32.14. The option became exercisable as to 25% of the shares on November 30, 2007, and became exercisable as to 1/48th of the shares each full month thereafter. /s/ Jason W. Radford, Attorney-in-fact 2016-01-14