Accrued Expenses and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Mar. 31, 2021	Dec. 31, 2020
Accrued expenses and other current liabilities:
Accrued compensation and benefits	$ 9,653	$ 15,207
Accrued consulting and professional fees	3,215	2,645
Accrued research and development expenses	3,821	2,222
Accrued revenue reserves	61,472	66,552
Accrued other	4,631	4,097
Total accrued expenses and other current liabilities	$ 82,792	$ 90,723