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Revenue Recognition (Details)
$ in Thousands
12 Months Ended
Oct. 28, 2020
USD ($)
day
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Disaggregation of Revenue [Line Items]        
Provision for revenue reserves to reduce product revenues to product revenues, net   $ 202,200 $ 105,900 $ 19,600
Deferred revenue, non-current   50,858 $ 0  
Collaborative Arrangement        
Disaggregation of Revenue [Line Items]        
Upfront payment receivable $ 50,000      
Contingent payments receivable upon achievement of development and regulatory milestones (up to) 39,000      
Contingent payments receivable upon achievement of commercial milestones (up to) $ 60,000      
Royalty percentage (in excess of) 25.00%      
Company's share of clinical trial costs, percentage 50.00%      
Collaborative agreement expiration, period after first commercial sale of product 12 years      
Collaborative agreement, termination by counterparty, effective after written notice period | day 180      
Repayment of upfront payment upon termination, percentage 85.00%      
Reimbursement of development expenses upon termination, percentage 50.00%      
Deferred revenue, non-current   $ 50,800    
Customer Concentration Risk | Sales Revenue, Net | Rhopressa | Distributor One        
Disaggregation of Revenue [Line Items]        
Concentration risk percentage   37.40% 36.50%  
Customer Concentration Risk | Sales Revenue, Net | Rhopressa | Distributor Two        
Disaggregation of Revenue [Line Items]        
Concentration risk percentage   32.40% 33.30%  
Customer Concentration Risk | Sales Revenue, Net | Rhopressa | Distributor Three        
Disaggregation of Revenue [Line Items]        
Concentration risk percentage   28.80% 28.00%