Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Total revenues, net	$ 20,081	$ 18,544	$ 58,455	$ 45,231
Costs and expenses:
Cost of goods sold	5,381	2,063	18,799	3,149
Selling, general and administrative	32,029	32,171	102,168	102,935
Pre-approval commercial manufacturing	110	5,841	2,304	16,117
Research and development	16,165	21,796	55,281	60,584
Total costs and expenses	53,685	61,871	178,552	182,785
Loss from operations	(33,604)	(43,327)	(120,097)	(137,554)
Other (expense) income, net	(6,044)	(6,075)	(16,900)	(7,053)
Loss before income taxes	(39,648)	(49,402)	(136,997)	(144,607)
Income tax benefit	0	0	(33)	(90)
Net loss	$ (39,648)	$ (49,402)	$ (136,964)	$ (144,517)
Net loss per common share—basic and diluted (in dollars per share)	$ (0.86)	$ (1.09)	$ (2.99)	$ (3.19)
Weighted average number of common shares outstanding—basic and diluted (in shares)	45,945,745	45,448,190	45,871,723	45,372,608
Net loss	$ (39,648)	$ (49,402)	$ (136,964)	$ (144,517)
Unrealized (loss) gain on available-for-sale investments, net	(129)	(158)	80	(158)
Comprehensive loss	(39,777)	(49,560)	(136,884)	(144,675)
Product revenues, net
Total revenues, net	$ 20,081	$ 18,544	$ 58,455	$ 45,231