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Accrued Expenses and Other Current Liabilities (Tables)
9 Months Ended
Sep. 30, 2020
Payables and Accruals [Abstract]  
Summary of Accrued Expenses and Other Current Liabilities
Accrued expenses and other current liabilities consist of the following:
(in thousands)SEPTEMBER 30, 2020DECEMBER 31, 2019
Accrued expenses and other current liabilities:
Accrued compensation and benefits $11,609 $11,169 
Accrued consulting and professional fees3,345 3,810 
Accrued research and development expenses (1)
4,379 8,734 
Accrued revenue reserves(2)
54,546 38,450 
Accrued other (3)
4,927 3,213 
Total accrued expenses and other current liabilities$78,806 $65,376 

(1)Comprised primarily of accruals related to fees for investigative sites, contract research organizations, contract manufacturing organizations and other service providers that assist in conducting preclinical research studies and clinical trials. Also included are liabilities incurred related to the Avizorex acquisition.
(2)Comprised primarily of accruals related to commercial and government rebates as well as returns.
(3)Comprised primarily of accruals related to interest payable as well as other business-related expenses.