Stock-Based Compensation - Allocated Expense (Detail) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense	$ 10,176	$ 10,695	$ 20,705	$ 23,315
Cost of goods sold
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense	670	0	1,167	0
Selling, general and administrative
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense	6,900	7,091	13,808	16,212
Pre-approval commercial manufacturing
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense	22	834	316	1,683
Research and development
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense	$ 2,584	$ 2,770	$ 5,414	$ 5,420