Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019
Total revenues, net	$ 18,033	$ 15,835	$ 38,374	$ 26,687
Costs and expenses:
Cost of goods sold	7,326	705	13,418	1,086
Selling, general and administrative	33,237	34,482	70,139	70,764
Pre-approval commercial manufacturing	80	5,819	2,194	10,276
Research and development	19,943	20,904	39,116	38,788
Total costs and expenses	60,586	61,910	124,867	120,914
Loss from operations	(42,553)	(46,075)	(86,493)	(94,227)
Other (expense) income, net	(5,634)	(1,089)	(10,856)	(978)
Loss before income taxes	(48,187)	(47,164)	(97,349)	(95,205)
Income tax benefit	0	0	(33)	(90)
Net loss	$ (48,187)	$ (47,164)	$ (97,316)	$ (95,115)
Net loss per common share—basic and diluted (in dollars per share)	$ (1.05)	$ (1.04)	$ (2.12)	$ (2.10)
Weighted average number of common shares outstanding—basic and diluted (in shares)	45,876,106	45,397,024	45,834,305	45,334,191
Net loss	$ (48,187)	$ (47,164)	$ (97,316)	$ (95,115)
Unrealized gain on available-for-sale investments, net	237	0	209	0
Comprehensive loss	(47,950)	(47,164)	(97,107)	(95,115)
Product revenues, net
Total revenues, net	$ 18,033	$ 15,835	$ 38,374	$ 26,687