Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019
Total revenues, net	$ 20,341	$ 10,852
Costs and expenses:
Cost of goods sold	6,092	381
Selling, general and administrative	36,902	36,282
Pre-approval commercial manufacturing	2,114	4,457
Research and development	19,173	17,884
Total costs and expenses	64,281	59,004
Loss from operations	(43,940)	(48,152)
Other (expense) income, net	(5,222)	111
Loss before income taxes	(49,162)	(48,041)
Income tax (benefit) expense	(33)	(90)
Net loss	$ (49,129)	$ (47,951)
Net loss per common share—basic and diluted (in dollars per share)	$ (1.07)	$ (1.06)
Weighted average number of common shares outstanding—basic and diluted (in shares)	45,792,504	45,270,660
Net loss	$ (49,129)	$ (47,951)
Unrealized (loss) gain on available-for-sale investments	(28)	0
Comprehensive loss	(49,157)	(47,951)
Product revenues, net
Total revenues, net	$ 20,341	$ 10,852